Vitamin B12 Deficiency: What are the consequences?

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Scientific publications: Vitamin B12 deficiency and Hypothyroidism

  1. Ayav A, Alberto JM, Barbe F, Brunaud L, Gerard P, Merten M, Gueant JL. Defective remethylation of homocysteine is related to decreased synthesis of coenzymes B2 in thyroidectomized rats. Amino Acids. 2005 Feb;28(1):37-43. Epub 2005 Jan 13

  2. Jabbar A, Yawar A, Waseem S, Islam N, Ul Haque N, Zuberi L, Khan A, Akhter J. Vitamin B12 deficiency common in primary hypothyroidism. J Pak Med Assoc. 2008 May;58(5):258-61. Erratum in: J Pak Med Assoc. 2009 Feb;59(2):126. Wasim, Sabeha [corrected to Waseem, Sabiha].

  3. Varghese AI, Varughese GI. Low serum vitamin B12 in older people: the role of alcohol and thyroid status. Age Ageing. 2007 Mar;36(2):231-2; author reply 232. Epub 2007 Jan 17.

  4. Govindarajan R, Galpin OP. Coexistence of Addison's disease, ulcerative colitis, hypothyroidism and pernicious anemia. J Clin Gastroenterol. 1992 Jul;15(1):82-3

  5. Stokstad EL, Nair CP. Effect of hypothyroidism on methylmalonate excretion and hepatic vitamin B-12 levels in rats. J Nutr. 1988 Dec;118(12):1495-501

  6. Carmel R, Spencer CA. Clinical and subclinical thyroid disorders associated with pernicious anemia. Observations on abnormal thyroid-stimulating hormone levels and on a possible association of blood group O with hyperthyroidism. Arch Intern Med. 1982 Aug;142(8):1465-9

  7.  Stokstad EL, Nair CP. Effect of hypothyroidism on methylmalonate excretion and hepatic vitamin B-12 levels in rats. J Nutr. 1988 Dec;118(12):1495-501

  8. Carmel R, Spencer CA. Clinical and subclinical thyroid disorders associated with pernicious anemia. Observations on abnormal thyroid-stimulating hormone levels and on a possible association of blood group O with hyperthyroidism. Arch Intern Med. 1982 Aug;142(8):1465-9.

  9. Orzechowska-Pawilojc A, Sworczak K, Lewczuk A, Babinska A. Homocysteine, folate and cobalamin levels in hypothyroid women before and after treatment. Endocr J. 2007 Jun;54(3):471-6. Epub 2007 Apr 27.

  10. Yammani RR, Seetharam S, Seetharam B. Cubilin and megalin expression and their interaction in the rat intestine: effect of thyroidectomy. Am J Physiol Endocrinol Metab. 2001 Nov;281(5):E900-7.

  11. Diekman MJ, van der Put NM, Blom HJ, Tijssen JG, Wiersinga WM. Determinants of changes in plasma homocysteine in hyperthyroidism and hypothyroidism. Clin Endocrinol (Oxf). 2001 Feb;54(2):197-204.

  12. Lien EA, Nedrebø BG, Varhaug JE, Nygård O, Aakvaag A, Ueland PM. Plasma total homocysteine levels during short-term iatrogenic hypothyroidism. J Clin Endocrinol Metab. 2000 Mar;85(3):1049-53.

  13. Nedrebø BG, Ericsson UB, Nygård O, Refsum H, Ueland PM, Aakvaag A, Aanderud S, Lien EA. Plasma total homocysteine levels in hyperthyroid and hypothyroid patients. Metabolism. 1998 Jan;47(1):89-93.

  14. Chan MM, Stokstad EL. Metabolic responses of folic acid and related compounds to thyroxine in rats. Biochim Biophys Acta. 1980 Oct 1;632(2):244-53.